The Oxford Thesaurus An A-Z Dictionary of Synonyms - vicissituden.

1) change, mutation, alteration, changeability, mutability, variation, variability, variety, alternation, flux, fluctuation, unpredictability: Who seeks stability in life often encounters its vicissitude. 2) vicissitudes. fluctuations, changes, variations, contrasts, inconstancy, unpredictability, uncertainties, Colloq ups and downs, flukiness: His success is amazing in light of the vicissitudes he survived.